Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New root canal filler could improve tooth survival

NCT ID NCT06252337

Disease control Sponsor: University of Bologna Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two root canal filling techniques: one using a newer bioceramic sealer and another using a traditional epoxy resin sealer. Researchers will track 80 healthy adults over two years to see which method leads to better healing and tooth survival. The goal is to find out if the newer material offers any advantage.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bioceramic sealer and epoxy resin sealer
What this could lead to
If successful, this could show that a newer bioceramic sealer works as well as or better than traditional materials for root canal treatments.
What could go wrong
This is a small, early-stage study with only 80 participants, so results may not apply to everyone. Differences between techniques might be small or not meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-75 years 2. Healthy status (ASA 1 or 2) 3. At least one tooth affected by endodontic pathology (pulpitis, pulp necrosis, re-exacerbated lesions with a previous root canal treatment) (b) Exclusion Criteria: 1. Teeth with less than 2 walls of crown structural integrity 2. Teeth used as abutments for fixed rehabilitation 3. Presence of active periodontal disease (PPD \> 4 mm, general BoP \> 25% of the sites) 4. Wide apexes (\>40 diameters) or absence of radiographic pulp chamber 5. Any systemic pathology that could compromise bone healing or the immune response (i.e., diabetes) 6. Pregnancy or breastfeeding 7. Heavy smoking (\>15 cigarettes/day) 8. Exposure to radiation therapy focused on the head and neck region and malignant disease directly involving the jaws. 9. Lack of occlusal contacts

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Bioceramic sealers are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Periapical Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bioceramic sealers Healing rate Periapical diseases Survival rate

Contacts and locations

Locations

  • Endodontic clinical section, DIBINEM, UNiversity of Bologna

    Bologna, 40125, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.