Chill out: cold water may soothe root canal pain
NCT ID NCT07598188
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using very cold water (around 2-5°C) to rinse the tooth during a root canal can lower pain after the procedure. Sixty adults with an infected tooth will be randomly assigned to get either room-temperature or cold rinse. Their pain will be checked before the treatment and again at 24 and 48 hours. The goal is to find a simple way to make root canals more comfortable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jul 2026
An estimate. Start dates often move.
- Expected to finish
-
Mar 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Individual (male/female) with age \>18 years with symptomatic apical periodontitis in permanent teeth Exclusion Criteria: 1. Teeth with calcified canals or aberrant root anatomy, 2. Female Pregnant patients 3. Patients using medications such as analgesics or anti-biotics drugs and 4. Those who refuse to participate in the study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Periapical diseases are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Islamabad Dental Hospital
Islamabad, Federal, 44000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can sonic and laser devices revolutionize root canal healing?
- Can a paste save infected baby teeth without extraction?
- AI trained to spot hidden tooth infections on routine x-rays
- Which filling heals tooth infections better? new study to find out
- Can a Blood-Derived gel save infected teeth after failed root canals?
- New root canal filler could improve tooth survival