Va Office Of Research And Development

This study tested a special grape seed extract (leucoselect phytosome) given before surgery to people with early-stage lung cancer. The goal was to see if it was safe and could slow tumor growth. Only 6 people took part, and the study was stopped early, so we don't have clear ans…

This study tested whether two specific antibiotics—fidaxomicin and a special vancomycin regimen—work better than standard vancomycin for people with repeat Clostridium difficile infections. The goal was to see which treatment best stops symptoms and prevents the infection from co…

This study looked at whether oxytocin, a natural brain chemical that helps with social bonding, could improve social functioning in veterans with schizophrenia. Researchers planned to give oxytocin and use brain scans to see who might benefit. The study was stopped early, so resu…

This study aimed to see if adding Problem Solving Therapy to standard suicide safety planning could reduce suicidal thoughts in older veterans (age 55+) with depression, anxiety, or PTSD. The trial planned to enroll 117 veterans but was terminated early. The approach focused on t…

This study tested whether a brief 4-session version of cognitive-behavioral therapy (CBT) works as well as the standard 6-session version for treating insomnia in veterans. Insomnia is very common among veterans and can harm daily life and health. The study enrolled 15 veterans w…

This study looked at why erythropoietin (EPO), a drug used to treat anemia, can raise blood pressure in people with chronic kidney disease. Researchers planned to enroll 160 participants but stopped early with only 27. The goal was to measure changes in blood pressure and blood v…

This study aimed to see if a simple brain-wave test (LDAEP) could predict which veterans with PTSD or depression would improve with the SSRI medication sertraline (Zoloft). Participants took sertraline or a placebo for 14 weeks while researchers measured their brain activity and …

This study looked at whether a non-invasive magnetic brain stimulation technique called iTMS, combined with hand exercises, could help people with spinal cord injury regain grasping ability. Researchers measured changes in brain signals and hand strength. The trial was terminated…

This small pilot study looked at whether a home-based conservative care plan is practical and acceptable for people with advanced chronic kidney disease who decide against dialysis. Researchers interviewed patients, their caregivers, and doctors to understand their experiences an…

This study tested whether short, repeated sessions of mild oxygen shortage (called acute intermittent hypoxia) combined with hand exercises could improve grip and pinch strength in people with chronic cervical spinal cord injury. The trial was early-stage and aimed at understandi…

This study tested a smartphone-based program to help veterans with serious mental illness (like PTSD, bipolar disorder, or schizophrenia) better recognize and describe their emotions. The goal was to see if improving emotion awareness could lower suicide risk. Only 11 veterans to…