Va Office Of Research And Development

This study tested whether two specific antibiotics (fidaxomicin and vancomycin followed by a taper) work better than standard vancomycin for treating repeat Clostridium difficile infections. About 308 adults with confirmed C. diff took part. The goal was to see which treatment pr…

This study looked at whether a shorter, 4-session version of cognitive-behavioral therapy for insomnia (CBT-I) works as well as the standard 6-session version in veterans. Insomnia is common in veterans and can harm daily life and health. The goal was to see if the brief therapy …

This study looked at whether oxytocin, a natural brain chemical that helps with social bonding, could improve social skills in veterans with schizophrenia. Researchers planned to give oxytocin and use brain scans to see who might benefit. The study was stopped early, so results a…

This study aimed to see if adding Problem Solving Therapy to standard suicide safety planning could reduce suicidal thoughts in older veterans (age 55+) with depression, anxiety, or PTSD. The trial planned to enroll 117 veterans but was terminated early. The approach focused on t…

This small pilot study looked at whether a home-based care plan is practical and acceptable for people with advanced chronic kidney disease who decide not to start dialysis. Researchers interviewed patients, their caregivers, and doctors to understand their experiences and challe…

This study aimed to see if a brief screening method could predict which veterans with PTSD or major depression would respond well to SSRI antidepressants. Researchers planned to enroll 94 participants over about 5 years, but the study was terminated early after enrolling only 26.…