Uppsala University

This 52-week trial tests whether combining a structured lifestyle program with a mushroom-based supplement and the drug bupropion helps overweight adults lose weight and lower cardiometabolic risk. About 250 adults aged 18 to 55 with a BMI between 25 and 35 will be randomly assig…

This study compares two types of back surgery for teens and young adults with scoliosis (a curved spine). One is the standard open surgery, and the other is a newer, minimally invasive approach that uses smaller cuts and advanced imaging. The goal is to see if the less invasive m…

This study tests a 13-week remote stress recovery program for people who had a heart attack before age 55 and still feel distressed. The program includes online sessions with a therapist, a workbook, and videos. The goal is to see if a larger trial is possible by checking how man…

This study tests a program called EMBER-IPV, designed to help women use their inner strengths to recover after intimate partner violence. About 150 women who experienced abuse in the past two years will fill out questionnaires before, during, and after the program to track change…

This study compares three online treatments for people with clinical burnout who are on sick leave or struggling at work. 210 adults in Sweden will receive either acceptance and commitment therapy (ACT), a recuperation-focused program, or ACT plus extra work support. The goal is …

Researchers are examining whether people with red hair or specific MC1R gene variants have more complications from anesthesia during surgery or medical procedures. The study uses health records from 100,000 people in Sweden and the UK, linking genetic data to outcomes like death,…

This study tests a program called EMBER designed to help women who have experienced intimate partner violence build resilience and improve their well-being. Eight women will take part in the program and answer weekly questionnaires about their resilience and health. Researchers w…

This observational study will collect blood samples from 25,000 adult ICU patients in Sweden to look for genetic variants linked to severe illness from infections, sepsis, or organ failure. Participants also give samples 3-6 months after leaving the hospital. The goal is to build…

This study looks at whether a skin monitor can reliably measure pain in newborns after surgery. Since babies can't tell us they're in pain, doctors currently use checklists and vital signs. The monitor tracks skin conductance, a sign of stress. Researchers will compare it to stan…

This trial in a Tanzanian refugee camp will test two programs for caregivers: a stress management course (Self Help Plus) and a parenting class (ICC-P). Researchers want to see if these programs improve children's emotional and behavioral health. About 324 families with children …