Uppsala University
Clinical trials sponsored by Uppsala University, explained in plain language.
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Head-to-Head diabetes drug trial aims to prevent heart attacks and kidney damage
Disease control CompletedThis large, completed study directly compared two common type 2 diabetes medications—dapagliflozin and metformin—to see which one is better at preventing serious long-term health problems. It involved over 2,000 adults with early-stage diabetes who were either new to medication o…
Phase: PHASE4 • Sponsor: Uppsala University • Aim: Disease control
Last updated Apr 04, 2026 03:49 UTC
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Gentler vein harvesting tested to make heart bypass grafts last longer
Disease control CompletedThis study aimed to see if a gentler method for taking a leg vein for heart bypass surgery leads to better long-term results than the standard method. It involved 902 patients who needed a first-time, non-emergency bypass operation. Researchers compared how often the bypass graft…
Phase: NA • Sponsor: Uppsala University • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New hip implant design aims to stop dislocations in elderly fracture patients
Disease control CompletedThis study tested whether a special 'dual mobility' hip implant cup is better than a standard cup at preventing the hip from dislocating after replacement surgery. It involved 1,600 elderly patients who needed a hip replacement due to a broken hip. Researchers randomly assigned p…
Phase: NA • Sponsor: Uppsala University • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Man's best friend helps kids get back to school
Symptom relief CompletedThis study tested whether trained social service dogs could help children who struggle to attend school. Researchers compared 64 children who received support from dog teams to children who received support from special education teachers. The goal was to see if spending time wit…
Phase: NA • Sponsor: Uppsala University • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Digital therapy offers new hope for burnout sufferers
Symptom relief CompletedThis small pilot study tested a new online therapy program designed to help people with severe burnout and exhaustion disorder. The program combined internet-based cognitive behavioral therapy with other support methods. Researchers aimed to see if this more focused digital appro…
Sponsor: Uppsala University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Scientists scan brains to see how caffeine changes anxiety and decisions
Knowledge-focused CompletedThis study aimed to understand how caffeine affects the brain, anxiety levels, and decision-making. Researchers compared 42 people with panic disorder to healthy individuals, giving them either caffeine or a placebo pill. They used advanced brain scans and tasks to measure reacti…
Phase: NA • Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Scientists track COVID's hidden damage in ICU patients
Knowledge-focused CompletedThis study aimed to understand how COVID-19 causes organ damage in critically ill patients. Researchers followed 380 patients in intensive care with suspected or confirmed COVID-19, collecting daily blood, urine, and sputum samples. They analyzed these samples to identify biologi…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Researchers map hidden risk for critically ill kids
Knowledge-focused CompletedThis study aimed to understand how often children in Swedish pediatric intensive care units (PICUs) experience delirium, a serious state of sudden confusion. Researchers followed 676 children to measure how common it was and to identify which factors, like certain illnesses or tr…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists search for Fibromyalgia's hidden clues in blood and brain
Knowledge-focused CompletedThis study aimed to understand how certain immune system proteins (autoantibodies) relate to fibromyalgia symptoms. Researchers compared 164 female participants—fibromyalgia patients with high or low antibody levels and healthy controls—using blood tests, skin samples, and brain …
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Researchers ask: how reliable is a common balance test for chronic pain?
Knowledge-focused CompletedThis study aimed to check how reliable a specific balance test is for people with long-term pain and to understand their personal experiences with balance. Researchers tested 73 adults with chronic pain, having some take the test twice and others discuss their feelings about it. …
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC