University Of Utah

Researchers are testing whether combining ribociclib and belinostat can help people with metastatic triple-negative breast cancer or recurrent ovarian cancer. The trial starts by finding the safest dose of the drug pair, then expands to see how well it works in breast cancer pati…

This phase II study tests two staggered schedules of the immunotherapy drug durvalumab combined with standard chemotherapy (pemetrexed and carboplatin) in 43 adults with advanced non-squamous non-small cell lung cancer. The goal is to see if changing the timing of the drugs impro…

This study tested a drug called selinexor in 17 people with a rare bone marrow cancer (myelofibrosis) that did not respond to or could not tolerate standard JAK inhibitor treatments. The main goal was to see if the drug could shrink an enlarged spleen by at least 35%. The trial w…

This early-stage trial tested a combination of two drugs, trametinib and hydroxychloroquine, in 25 adults with advanced pancreatic cancer that could not be removed by surgery. The main goal was to find the safest dose and understand side effects. The study was stopped early, so r…

This study tested a special ultrasound that uses a contrast dye to get clearer images of a new kidney after transplant. The goal was to see if this method could help doctors find early signs of problems like rejection or slow function. The study was small (20 people) and was stop…

This study aimed to see if changing meal timing could lower cancer risk in Native Hawaiian and Pacific Islander women. Only 2 women joined before the study was stopped early. The goal was to find a culturally fitting way to reduce cancer risk factors like obesity and diabetes in …

This study tests whether a headband with special semiconductors can help with memory and thinking problems (often called 'chemo brain') in people who have had breast or gynecologic cancer. About 50 participants will wear either the active headband or a placebo version for 18 hour…

This phase II trial tested whether Swedish massage can reduce fatigue in men who have had radiation for prostate cancer. The study enrolled 28 men aged 45 and older who reported significant fatigue. Researchers measured fatigue levels and inflammatory markers before and after mas…

This study compared two heat-based procedures to treat pain from the sacroiliac joint, a common cause of low back pain. One method uses a newer device to create larger burns, while the other uses a standard technique. The trial enrolled 20 adults with long-term pain who had not i…

This study looked at whether a supplement called Q-Urol (made from quercetin, bromelain, rye flower pollen, and papain) could reduce prostate inflammation caused by radiation therapy in men with localized prostate cancer. Ten men who had brachytherapy (with or without other radia…