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New drug combo trial for tough pancreatic cancer shows early promise

NCT ID NCT03825289

First seen May 15, 2026 · Last updated Jun 15, 2026 · Updated 7 times

Summary

This early-stage trial tested a combination of two drugs, trametinib and hydroxychloroquine, in 25 adults with advanced pancreatic cancer that could not be removed by surgery. The main goal was to find the safest dose and understand side effects. The study was stopped early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.