University Of Southern California

This study tested whether a once-daily extended-release form of tacrolimus (Envarsus XR) combined with azathioprine works as well as the standard twice-daily tacrolimus with mycophenolate for preventing kidney transplant rejection. The trial planned to enroll 20 kidney transplant…

This pilot study tested a new drug called sEphB4-HSA combined with standard chemotherapy (azacitidine or decitabine) in 7 adults with myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia that had returned or not responded to prior treatment. The go…

This small phase II study tested whether combining the chemotherapy drug docetaxel with the targeted therapy lapatinib could help patients with advanced bladder cancer that had already been treated with platinum-based chemo. Only 15 people enrolled before the study was terminated…

This study looked at whether combining mammography and breast MRI can help doctors identify patients with ductal carcinoma in situ (DCIS) who could be treated with a single dose of radiation during surgery. The goal was to see if this approach could reduce the need for additional…

This study tested a combination of two drugs, bortezomib and docetaxel, in 15 men with advanced prostate cancer that had stopped responding to hormone therapy. The goal was to see if the drugs could lower PSA levels and ease pain. The trial was terminated early, so the findings a…

This study tested whether taking the steroid oxandrolone for 12 weeks after rotator cuff repair could improve tendon healing and muscle mass. Only 4 people participated before the trial was stopped early. Because it was so small, we cannot draw any reliable conclusions about whet…

This study tested whether bringing a team of doctors, nurses, social workers, and chaplains into the home could improve symptoms and quality of life for people with cancer, heart failure, or COPD. The goal was to enroll over 1,100 patients, but the trial was terminated early and …

This study tested whether consumer movement trackers can more accurately measure physical function in cancer patients compared to the standard ECOG performance status scale. Researchers used a Kinect device to record patients performing simple movements like standing up and walki…

This study looked at whether movement and fitness trackers can give a more accurate measure of how well cancer patients are functioning physically during early-phase clinical trials. Researchers wanted to see if tracker data could help identify patients at higher risk for serious…