University Hospital Southampton Nhs Foundation Trust

This study tests a new blood test called Avantect to see if it can find pancreatic cancer early in people aged 50-84 who were diagnosed with type 2 diabetes in the last 6 months. About 15,000 participants will give blood samples and fill out anxiety questionnaires over a year. Th…

This study tests a small, sticky chest sensor called PneumoRator that measures breathing rate continuously. 50 adults having major surgery will wear the device before, during, and after their operation. Researchers will compare its readings to standard hospital methods to see if …

This study tests whether a questionnaire that measures how confident teens feel about managing their asthma can help doctors give better support. About 98 teenagers aged 12-18 with asthma will either get this tailored approach or a standard check-up. After three months, researche…

This study aims to find better ways to diagnose heavy menstrual bleeding, which affects 1 in 3 women. Researchers will use wearable sensors and MRI scans to measure uterine activity and look for differences between people with and without heavy bleeding. The goal is to develop a …

This study watches 160 people with oesophageal cancer to see if an endoscopic ultrasound (EUS) scan, done after standard CT-PET scans, changes their treatment plan. Researchers will also interview patients and doctors to understand their views on using EUS. The goal is to learn w…

This study looks at whether an implantable heart device (ICD) helps people with non-ischemic cardiomyopathy—a type of heart failure not caused by blocked arteries—live longer. About 2,500 participants will be split into two groups: one gets the device, the other does not. The goa…

This study looks at how immunotherapy for advanced cancer changes a person's physical fitness and quality of life. About 67 adults with solid tumors will take fitness tests and answer questionnaires before starting treatment and again 12 weeks later. Researchers will also track l…

This study looks at people who had a major heart attack (STEMI) and have other blockages in their heart arteries. Doctors want to find out which of these extra blockages are likely to cause future problems and which are safe to treat with medication alone. Using CT scans and bloo…

This study aims to understand the personal experiences of adults with primary ciliary dyskinesia (PCD) regarding fertility, pregnancy, and parenthood. Researchers will interview 30 people in the UK who have a confirmed or likely PCD diagnosis. The goal is to gather insights that …

This study tests whether a virtual group class (GoPREPARE) that teaches exercise, nutrition, and emotional support before cancer surgery is practical and helpful. About 24 adults awaiting surgery will be randomly assigned to the class or standard care. Researchers will track how …