University Hospital Southampton Nhs Foundation Trust

This study is testing a new blood test called Avantect to see if it can find pancreatic cancer early in people who were diagnosed with type 2 diabetes in the last 6 months. About 15,000 adults aged 50-84 will give blood samples and fill out anxiety questionnaires over a year. The…

This study tests a new way to help teenagers with asthma feel more in control of their condition. Teens aged 12-18 will either get a standard doctor visit or a visit where their confidence in managing asthma is assessed and addressed. After three months, researchers will compare …

This study watches how immunotherapy affects physical fitness and daily life in 67 adults with advanced solid cancers. Participants do fitness tests and fill out questionnaires before starting treatment and again 12 weeks later. Researchers also take blood samples and follow heal…

This study looks at whether implantable defibrillators (ICDs) help people with heart failure that is not from blocked arteries live longer. About 2,500 participants will be split into two groups: one gets an ICD, the other does not. Researchers will track survival and quality of …

This study observes 160 adults with oesophageal cancer to see if an endoscopic ultrasound (EUS) changes their treatment plan after standard scans. Researchers will also interview patients and doctors to understand their views on using EUS. The goal is to learn when this test is m…

This study looks at whether vaginal fluid can help find gynecological cancers early. Researchers will compare samples from 250 people with and without cancer to spot changes in markers. The goal is to create a simple, non-invasive test for early detection and monitoring.

This study tests a virtual group class called GoPREPARE that helps people get ready for major cancer surgery. The class covers exercise, nutrition, and emotional support to reduce complications and speed recovery. Researchers will recruit 24 adults awaiting surgery and randomly a…

This study tests a small, sticky chest sensor called PneumoRator that measures breathing rate continuously. Researchers will put it on 50 patients before major surgery and compare its readings to standard hospital monitors. The goal is to see if the device is accurate and comfort…

This study looks at people who had a major heart attack (STEMI) and have other narrowed arteries that did not cause the attack. Doctors want to learn which of these other narrowings are likely to cause future problems, like another heart attack or chest pain. Using CT scans and b…

This study aims to understand why some women experience heavy menstrual bleeding (HMB), which affects 1 in 3 women. Researchers will use wearable sensors and MRI scans to measure uterine activity and compare findings between women with and without HMB. The goal is to lay the grou…

This study will interview 30 adults in the UK who have primary ciliary dyskinesia (PCD), a rare condition affecting the lungs and other organs. Researchers want to learn about their personal experiences with fertility, pregnancy, and parenthood. The goal is to better understand t…