University Hospital, Bordeaux

This study is testing whether adding the diabetes medication metformin to standard methotrexate treatment works better for controlling rheumatoid arthritis. Researchers want to see if the combination helps more patients achieve remission compared to methotrexate alone. The trial …

This study is for people with rheumatoid arthritis (RA) who haven't gotten enough relief from their current biologic or targeted drugs. It's testing if taking two powerful medications together—baricitinib and an anti-TNF drug—works better to control the disease than taking just b…

This study aims to find the best treatment approach for patients with non-small cell lung cancer that has spread to the brain in a limited way (fewer than 5 spots). Researchers are comparing two strategies: treating the main tumor and brain spots directly versus using body-wide m…

This study is testing whether combining two drugs, spartalizumab and pazopanib, can help control advanced solid tumors that have come back or stopped responding to standard treatments. It will enroll about 80 children and adults to find the safest dose for kids and see if the com…

This study is testing whether virtual reality (VR) therapy can help people feel better about their bodies after they have had major weight loss (bariatric) surgery. It compares a special VR program designed to help patients accept their new body shape against the standard follow-…

This study aims to understand how thinking and memory problems develop over time in people with primary progressive multiple sclerosis (PPMS). Researchers will follow 66 participants for 2 years, using brain scans and detailed thinking tests to see how brain changes relate to cog…

This study aims to find out if routinely screening for hidden heart disease in people with type 2 diabetes who are at very high risk is a good use of healthcare resources. Researchers will analyze the health records of 90,000 French patients to compare the costs and outcomes of t…

This study aims to find better ways to identify which people with lupus are most likely to develop heart disease. Researchers will follow 500 adult lupus patients, measuring specific substances in their blood and using ultrasound to track artery health over time. The goal is to d…

This study aims to understand why some organ transplant patients develop severe, hard-to-treat Cytomegalovirus (CMV) infections. Researchers are collecting blood samples and health data from over 550 transplant patients across Europe. By studying these samples, they hope to ident…