Universitätsklinikum Hamburg-eppendorf

This study aimed to check how long the Ebola vaccine (VSV-EBOV) protects people at risk of exposure, like lab workers or healthcare staff. It also planned to test if a booster shot strengthens immunity. The trial was withdrawn before enrolling any participants, so no results are …

This trial is testing whether giving children with medulloblastoma a lower dose of radiation and less intense chemotherapy can still cure the cancer while causing fewer long-term side effects. It includes 360 children aged 3 to 21 with specific genetic types of the tumor. The app…

This study tests a combination of four drugs (isatuximab, carfilzomib, lenalidomide, and dexamethasone) in people newly diagnosed with a high-risk form of multiple myeloma. The goal is to see if this intensive treatment can make the cancer undetectable at a deep level. 246 partic…

This study compares two ways to replace a narrowed heart valve in people with severe aortic stenosis who are at intermediate risk for surgery. About 1,400 participants will be randomly assigned to get either a less invasive TAVI procedure or open-heart surgery (SAVR). The main go…

This study tests a web-based tool called gp-multitool.de that helps general practitioners follow guidelines for older patients with multiple chronic conditions. About 659 patients from GP practices in Germany are taking part. The tool lets patients fill out questionnaires online …

This study analyzes data from 423 patients to develop a new scoring system called MASCAN, which aims to predict when facemask ventilation will be difficult during anesthesia. Researchers will test how well the score works by comparing it to actual events recorded in patient chart…

This study looks at data from 1,785 patients who had a breathing tube placed for surgery. The goal is to create a standard set of information that doctors can use to alert future teams if a patient had a difficult airway. This could help prevent complications in later procedures.

This study uses brain scans to see how the brainstem and other brain areas respond to mild electrical pulses on the face and arm in 40 healthy volunteers. The goal is to better understand the brain circuits involved in facial pain and touch, which could help future research on mi…

This study looks at whether brain scans can help predict which people with migraine will respond to a class of drugs called CGRP antibodies. Researchers used MRI to measure brain structure, activity, and blood flow in 219 adults with frequent migraine before and after 12 weeks of…