Healthy volunteers help scientists map Brain's pain pathways for migraine insights
NCT ID NCT06535880
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses brain scans to see how the brainstem and other brain areas respond to mild electrical pulses on the face and arm in 40 healthy volunteers. The goal is to better understand the brain circuits involved in facial pain and touch, which could help future research on migraine disorders. Participants must be healthy, suitable for MRI, and free of headache or psychological conditions.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy * suitable fo MRI Exclusion Criteria: * headache disease * psychological disorder * pregnancy * all exclusion criteria necessary for imaging in a 3 T MRI scanner
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Medical Center Hamburg-Eppendorf
Hamburg, 20246, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a symptom registry unmask hidden migraine variants?
- Melatonin may double up against childhood migraines