The University Of Queensland

This study tests whether metformin, a drug used for diabetes, can slow the loss of kidney function in people with early-stage autosomal dominant polycystic kidney disease (ADPKD). About 1,174 adults aged 18-70 with mild to moderate kidney decline will take metformin or a placebo …

This study tests whether using a person's genetic information to determine the dose of the antifungal drug voriconazole leads to better drug levels in the blood compared to standard dosing. About 104 children and adults with blood cancer and a fungal infection will take part. The…

This study tests a special device called PIVO Pro that lets doctors draw blood for infection tests through an IV line already in the arm, avoiding extra needle sticks. The goal is to see if this method reduces contamination of the blood sample compared to the usual way. About 1,1…

This study tests whether reducing anti-rejection drugs, with or without an extra treatment called IVIG, can better control BK virus in kidney transplant patients. BK virus can damage the new kidney and lead to transplant failure. About 280 adults and children who have a kidney or…

This study tests whether giving pasteurized donor human milk to full-term babies of mothers with diabetes during the first five days of life can reduce the number of infants admitted to the neonatal unit for low blood sugar. About 1,444 mothers and their newborns will be randomly…

This study is for people with a hard-to-treat lung infection called MABS. It compares different drug combinations to find which works best to clear the infection while causing the fewest side effects. About 300 adults will take part, and the goal is to improve health and quality …

This study tests whether starting haemodialysis gradually (incremental dialysis) can help preserve quality of life and remaining kidney function in adults with kidney failure. About 372 people who are just beginning dialysis will take part. The goal is to see if this approach is …

This study tests whether starting peritoneal dialysis (a home-based treatment for kidney failure) at a low dose and gradually increasing it can improve patients' quality of life compared to the standard full-dose approach. About 224 adults new to dialysis will take part. The goal…