Could a slower start to dialysis protect quality of life?
NCT ID NCT04932148
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether starting haemodialysis gradually (incremental dialysis) can help preserve quality of life and remaining kidney function in adults with kidney failure. About 372 people who are just beginning dialysis will take part. The goal is to see if this approach is safe, practical, and better for patients and their families.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 372 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2022
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults (≥ 18 years of age) and 2. Commencing HD as their initial dialysis therapy and 3. Able to give informed consent Exclusion Criteria: 1. Urine output \<0.5Litres/day 2. Unlikely to be on HD for ≥1 year.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
18 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bundaberg Hospital
RECRUITINGBundaberg, Queensland, Australia
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Cairns Hospital
RECRUITINGCairns, Queensland, Australia
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Concord Repatriation General Hospital
RECRUITINGConcord, New South Wales, 2139, Australia
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Eastern Health
RECRUITINGMelbourne, Victoria, Australia
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Fiona Stanley Hospital
NOT_YET_RECRUITINGMurdoch, Washington, 6150, Australia
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John Hunter Hospital
RECRUITINGNew Lambton Heights, New South Wales, 2305, Australia
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Liverpool Hospital
RECRUITINGLiverpool, New South Wales, 2170, Australia
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Logan Hospital
RECRUITINGLogan City, Queensland, 4131, Australia
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Monash Health
RECRUITINGMelbourne, Victoria, 3168, Australia
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Northern Beaches Hospital
NOT_YET_RECRUITINGFrenchs Forest, New South Wales, 2086, Australia
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Port Macquarie Hospital
RECRUITINGPort Macquarie, New South Wales, 2444, Australia
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Princess Alexandra Hospital
RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Redland Hospital
NOT_YET_RECRUITINGCleveland, Queensland, 4163, Australia
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Royal Adelaide Hospital
RECRUITINGAdelaide, South Australia, 5000, Australia
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Royal North Shore Hospital
NOT_YET_RECRUITINGSaint Leonards, New South Wales, 2065, Australia
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St George Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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Toowoomba Hospital
RECRUITINGToowoomba, Queensland, 4350, Australia
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University Health Network- University of Toronto
NOT_YET_RECRUITINGToronto, Ontario, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- How do HIV drugs behave when kidneys fail? study measures blood levels
- Can we predict who will progress quickly to kidney failure?
- Can a new preservation fluid keep donor kidneys healthier for transplant?
- Extra vaccine dose: could it shield dialysis patients from hepatitis b?
- Which emergency dialysis saves more lives? a new study investigates