The First Affiliated Hospital Of Guangzhou Medical University

This study tests whether a 'tubeless' anesthesia and surgery method helps adults with end-stage lung disease recover faster after a lung transplant. Instead of a breathing tube and deep sedation, patients breathe on their own during and after surgery. About 110 participants at se…

This study looks at whether keeping patients breathing on their own during lung transplant surgery can help them recover faster and survive better. It involves 40 adults with end-stage lung disease who need a rescue transplant. Researchers will track how many need a breathing tub…

This study looks at whether keeping patients breathing on their own during lung transplant surgery helps them recover faster. It involves 60 adults aged 70 and older with end-stage lung disease. The goal is to see if this approach reduces the need for a breathing machine after su…

This study tests a drug called golidocitinib in 16 people with advanced lung cancer who have severe blood problems caused by their immunotherapy. The goal is to see if the drug can safely reverse these blood side effects. Participants must be at least 18 and have stable cancer.

This study looks at whether a special breathing technique during and after lung transplant surgery can help very underweight patients recover faster. It involves 56 adults with end-stage lung disease and a very low body mass index. The goal is to see if this approach reduces the …

This study tests a new way to treat multiple ground-glass lung nodules—small spots that can turn into lung cancer. Patients inhale a mist containing a modified virus that delivers a healthy p53 gene to the lungs. The goal is to shrink or eliminate the nodules. About 38 adults wit…

This study is for people with advanced non-small cell lung cancer that has a specific change called HER2 (mutation, amplification, or overexpression) and has gotten worse after at least one prior treatment. Participants will receive two drugs, SHR-A1811 and pertuzumab, to see if …

This study tests a new way to treat people who have several lung nodules. It combines robot-assisted heat treatment or dye marking with a less invasive surgery that avoids a breathing tube. The goal is to see if this approach is safe and can be done successfully. About 30 adults …

This study tests a new drug called limertinib combined with radiation therapy as a first treatment for people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) that has spread to the brain. The goal is to see if the combination can better control brain …

This early-phase study tests a new treatment for people with operable non-small cell lung cancer. It combines NK010 immune cells, an immunotherapy drug (PD-1 antibody), and standard chemotherapy given before surgery to shrink tumors. The main goals are to check safety and see how…

This study looks at whether the shingles vaccine can prevent shingles and improve survival in 500 lung cancer patients. Researchers will track how many get shingles within a year and check survival rates over time. The goal is to see if the vaccine is safe and effective for this …

This study tests a 'tubeless' approach for people having minimally invasive lung surgery to remove small nodules. Instead of using breathing tubes and chest drains, the new method uses a simpler airway device and skips the chest tube. The goal is to see if this helps patients rec…

This study tests whether a Chinese herbal medicine called Lifei Qingchang Granules can help people with stable bronchiectasis breathe easier and feel better. About 150 adults who have had at least one flare-up in the past year will take either the granules or a placebo for 3 mont…

This study looks at whether avoiding a chest tube after keyhole lung surgery (VATS) helps patients recover faster and feel less pain. About 300 adults having a wedge resection for a lung nodule will be randomly assigned to one of three groups: standard chest tube, one-time suctio…

This study tests whether using a laryngeal mask (no breathing tube) during esophageal cancer surgery is as safe and effective as the standard method with a breathing tube. About 500 adults aged 18-75 with resectable esophageal cancer will be randomly assigned to one of two anesth…

This study compares a newer anesthesia method where patients breathe on their own during lung surgery to the traditional method using a breathing tube and machine. About 1,600 adults with small lung nodules will be randomly assigned to one of the two methods. The goal is to see i…