Swiss Cancer Institute

This study is testing a less intense combination of chemotherapy and radiation for people with stage IIA or IIB seminoma, a type of testicular cancer. The goal is to see if a milder treatment can still control the cancer while causing fewer side effects. About 135 participants wi…

This study tests whether giving denosumab every 12 weeks instead of every 4 weeks is just as effective at preventing bone complications (like fractures or spinal cord compression) in people with metastatic breast or prostate cancer. About 1,380 participants will be followed to co…

This study tests whether adding a special type of radiotherapy to standard chemotherapy and immunotherapy before surgery can help people with stage III lung cancer live longer without the cancer coming back. About 90 participants will receive one of three different radiation sche…

This study tests a personalized approach for people with a type of blood cancer called diffuse large B-cell lymphoma. Doctors use special blood tests (ctDNA) and PET scans after two rounds of standard chemo to decide if treatment should be adjusted—either stronger or milder. The …

This study tests whether adding chest radiation to an immunotherapy drug (durvalumab) after initial chemotherapy can help people with advanced small cell lung cancer live longer without the disease getting worse. About 46 adults with extensive-stage small cell lung cancer will re…

This trial tests whether giving a special BCG treatment directly into the bladder, followed by chemotherapy and immunotherapy, can make muscle-invasive bladder cancer disappear before surgery. The goal is to increase the chance of a complete response, so patients might avoid havi…

This study is testing a new liquid biopsy that looks for tumor DNA in spinal fluid to see if it can better detect lymphoma that has spread to the brain or spinal cord. Researchers will compare this test to standard methods in 64 people newly diagnosed with high-risk B-cell lympho…