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New combo therapy aims to extend life in aggressive lung cancer

NCT ID NCT04472949

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 31 times

Summary

This study tests whether adding chest radiation to an immunotherapy drug (durvalumab) after initial chemotherapy can help people with advanced small cell lung cancer live longer without the disease getting worse. About 46 adults with extensive-stage small cell lung cancer will receive four cycles of chemotherapy plus durvalumab, then those whose cancer responds will get durvalumab for up to two years along with chest radiation. The goal is to improve cancer control and survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • HFR Freiburg - Kantonsspital

    Villars-sur-Glâne, 1752, Switzerland

  • Hôpitaux Universitaires de Genève

    Geneva, 1211, Switzerland

  • IOSI Ospedale Regionale di Bellinzona e Valli

    Bellinzona, 6500, Switzerland

  • Inselspital Bern

    Bern, 3010, Switzerland

  • Kantonsspital - St. Gallen

    Sankt Gallen, CH-9007, Switzerland

  • Kantonsspital Aarau

    Aarau, CH-5001, Switzerland

  • Kantonsspital Graubuenden

    Chur, CH-7000, Switzerland

  • Kantonsspital Olten

    Olten, CH-4600, Switzerland

  • Kantonsspital Winterthur

    Winterthur, 8401, Switzerland

  • Klinik Hirslanden

    Männedorf, 8708, Switzerland

  • Regionalspital Thun

    Thun, 3600, Switzerland

  • Spital Männedorf

    Männedorf, 8708, Switzerland

  • Universitaetsspital Basel

    Basel, 4031, Switzerland

  • UniversitätsSpital Zürich

    Zurich, 8091, Switzerland

Conditions

Explore the condition pages connected to this study.