Swiss Cancer Institute

This study tests a new approach for people with high-risk soft tissue sarcoma in the arms, legs, or trunk. The treatment combines chemotherapy, targeted heat therapy (hyperthermia), radiation, and surgery before any other treatment. The goal is to see if this total neoadjuvant tr…

This study tests if injecting the drug INT230-6 into breast tumors before standard chemotherapy and immunotherapy can help eliminate all cancer in the breast and lymph nodes. About 61 people with early triple-negative breast cancer (a fast-growing type) will be randomly assigned …

This study looks at people with advanced stage IV non-small cell lung cancer that has spread. After initial drug therapy (chemo, immunotherapy, or targeted therapy) works well, half the participants will also get surgery or radiation to remove remaining tumor spots. The goal is t…

This study tests whether adding darolutamide to standard treatments (like chemotherapy or targeted therapy) can help men with a hard-to-treat form of advanced prostate cancer live longer without their cancer getting worse. About 162 participants will receive either standard care …

This study tests whether adding doxycycline, a common and safe antibiotic, to standard chemotherapy can better target cancer stem cells in early-stage ER+/HER2- breast cancer. About 50 participants will receive doxycycline alongside chemo before surgery. The goal is to see if thi…

This study tests whether terbinafine, a widely used antifungal pill, can slow the rise of PSA levels in men whose prostate cancer has returned after initial treatment. The trial enrolls 42 men with biochemical recurrence but no visible tumors on scans. The goal is to see if this …

This study tests whether a reduced dose of chemotherapy combined with the immunotherapy drug cemiplimab works better than cemiplimab alone for people aged 70 and older with advanced non-small cell lung cancer. Participants must be in relatively poor health or frail, and their tum…