Springworks Therapeutics, Inc., A Healthcare Company Of Merck Kgaa, Darmstadt, Germany
Clinical trials sponsored by Springworks Therapeutics, Inc., A Healthcare Company Of Merck Kgaa, Darmstadt, Germany, explained in plain language.
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Stomach acid pills may change how this drug works
Knowledge-focused CompletedThis study looked at how two common stomach acid reducers (famotidine and rabeprazole) affect the levels of the drug nirogacestat in the blood. Twenty-four healthy men took nirogacestat alone and with each acid reducer. The goal was to see if these stomach medications change how …
Phase: PHASE1 • Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Knowledge-focused
Last updated May 26, 2026 08:31 UTC
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Healthy men needed to test how a new drug changes other medications
Knowledge-focused CompletedThis study looked at how the drug nirogacestat affects the way the body processes five common medications in 20 healthy men. Participants took the five drugs alone and then again while also taking nirogacestat. The goal was to see if nirogacestat speeds up or slows down the break…
Phase: PHASE1 • Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Healthy volunteers help uncover drug interaction secrets
Knowledge-focused CompletedThis study looked at how a common seizure drug, carbamazepine, changes the amount of mirdametinib in the blood. 36 healthy adults took both drugs to see how the body processes them together. The goal was to understand potential drug interactions, not to treat any disease.
Phase: PHASE1 • Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Knowledge-focused
Last updated May 18, 2026 12:03 UTC