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New hope for rare tumor patients: drug trial targets desmoid growths without surgery

NCT ID NCT07170644

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 31 times

Summary

This study tests a drug called nirogacestat in 20 Japanese adults with desmoid tumors (also called aggressive fibromatosis) that are growing. The goal is to see if the drug can shrink or control these non-cancerous but painful tumors. Participants take the drug by mouth, and doctors monitor tumor size and side effects over time.

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Contacts and locations

Locations

  • Nagoya University Hospital

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Cancer Center Hospital

    Chuo Ku, Tokyo, 104-0045, Japan

  • Osaka Prefectural Hospital Organization Osaka International Cancer Institute

    Osaka, 541-8567, Japan

Conditions

Explore the condition pages connected to this study.