New hope for rare tumor patients: drug targets desmoid growth

NCT ID NCT07170644

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests a drug called nirogacestat in 20 Japanese adults with desmoid tumors that are growing. Desmoid tumors are non-cancerous but can cause pain and disability. The goal is to see if the drug can shrink or stop the tumors. Participants take the drug by mouth and are monitored for response and side effects.

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Contacts and locations

Locations

  • Nagoya University Hospital

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Cancer Center Hospital

    Chuo Ku, Tokyo, 104-0045, Japan

  • Osaka Prefectural Hospital Organization Osaka International Cancer Institute

    Osaka, 541-8567, Japan

Conditions

Explore the condition pages connected to this study.