Springworks Therapeutics, Inc., A Healthcare Company Of Merck Kgaa, Darmstadt, Germany

This study tests a drug called nirogacestat in 20 Japanese adults with desmoid tumors (also called aggressive fibromatosis) that are growing. The goal is to see if the drug can shrink or control these non-cancerous but painful tumors. Participants take the drug by mouth, and doct…

This study tests a daily pill called mirdametinib in 114 adults and children with neurofibromatosis type 1 (NF1) who have nerve tumors that cannot be surgically removed and are causing serious problems. The goal is to see if the drug can shrink these tumors by at least 20%. Parti…