Sidney Kimmel Comprehensive Cancer Center At Thomas Jefferson University

This study tested a two-step donor stem cell transplant in 51 people with high-risk blood cancers. The approach uses total-body radiation and chemo before the transplant to prepare the body, then donor stem cells are given to rebuild healthy blood cells and attack remaining cance…

This study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. The approach uses low-dose chemo and radiation before a donor stem cell infusion, followed by drugs to prevent graft-versus-host disease. The goal was to control the cancer…

This study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. The approach uses a drug called cyclophosphamide to lower the chance of graft-versus-host disease (GVHD), a serious side effect. The goal was to help more patient…

This study looked at whether giving a drug called cyclophosphamide after a stem cell transplant could help the new cells settle in better and reduce serious side effects like graft-versus-host disease (GVHD). It involved 78 people with blood cancers who received stem cells from a…

This study tested the drug nivolumab in 26 people who had surgery for stage IIB or IIC melanoma, a serious skin cancer. The goal was to see if the drug could help keep the cancer from coming back. Nivolumab is a type of immunotherapy that helps the immune system attack cancer cel…

This study tested a combination of two drugs, azacitidine and sirolimus, in 57 people with high-risk myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that had come back or was hard to treat. The goal was to see if the combination could stop cancer cells from growing…

This study looked at 77 people with multiple myeloma or non-Hodgkin lymphoma who had a stem cell transplant. Half got a growth factor (tbo-filgrastim) after transplant and half did not. The goal was to see if skipping the growth factor still allowed patients to leave the hospital…

This study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. First, patients got low-dose chemotherapy and radiation to prepare the body. Then, they received donor immune cells followed by donor stem cells to help destroy c…

This study tested a new approach for people whose head and neck cancer has come back. During surgery to remove the tumor, doctors placed tiny radioactive seeds (Cesium-131) directly into the area to kill any remaining cancer cells. The goal was to see if this internal radiation c…

This early study tested whether adding heat therapy (hyperthermia) to high-dose radiation is safe for men whose prostate cancer returned after previous radiation. Only 3 men took part, and the main goal was to see side effects. The approach aims to make cancer cells more sensitiv…

This pilot study tested a maskless immobilization device for 12 adults with head and neck cancer or brain tumors undergoing radiation therapy. The device aims to prevent movement during treatment with the same accuracy as standard thermoplastic masks, which can be uncomfortable. …

This study looked at whether taking vitamin B6 can reduce hot flashes in men with prostate cancer who are on hormone therapy (ADT). 43 men rated how bothersome their hot flashes were before and after 8 weeks of vitamin B6. The goal was to see if this simple supplement could impro…

This study tested whether an educational program in high-risk neighborhoods could increase men's knowledge about prostate cancer and screening. 239 men who lived in these areas took part. The goal was to see if learning about the pros and cons of screening would help them make cl…