Sidney Kimmel Comprehensive Cancer Center At Thomas Jefferson University
Clinical trials sponsored by Sidney Kimmel Comprehensive Cancer Center At Thomas Jefferson University, explained in plain language.
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Old drugs, new target: repurposing metformin and doxycycline to fight cancer
Disease control TerminatedThis study tested whether two existing, commonly used drugs—metformin (for diabetes) and doxycycline (an antibiotic)—could help treat head and neck cancer. It involved a small group of patients who were scheduled to have their tumors surgically removed. The goal was to see if tak…
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Drug cocktail aims to shrink tumors before lung cancer surgery
Disease control TerminatedThis study tested whether giving a combination of drugs before surgery could better treat early-stage lung cancer. The treatment included an immunotherapy drug (nivolumab) plus standard chemotherapy drugs. The goal was to shrink tumors before surgical removal, potentially improvi…
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Radiation and eye injections tested to save vision from rare eye cancer
Disease control TerminatedThis study tested a two-part treatment for a rare eye cancer called uveal melanoma. It combined precise radiation therapy with injections of a drug (aflibercept) into the eye. The goal was to see if this approach could control the tumor while better preserving the patient's visio…
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Mar 10, 2026 12:53 UTC
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Diabetes drug tested to ease harsh side effects of thyroid cancer therapy
Symptom relief TerminatedThis small, terminated study tested whether the common diabetes drug metformin could help reduce side effects for people with thyroid cancer undergoing radioactive iodine treatment. The goal was to see if metformin could protect blood cell counts and lessen symptoms like dry mout…
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC