Peking University Shenzhen Hospital

This early-phase study tests a new treatment called CAR-DC for people with advanced solid tumors (like lung, liver, or stomach cancer) that have not responded to standard care. The therapy uses a patient's own immune cells, modified in a lab to recognize and attack cancer cells. …

This study tests a drug called iruplinalkib in people with a specific type of advanced lung cancer (ALK-positive) that has stopped responding to a previous treatment called lorlatinib. The goal is to see how well iruplinalkib controls the cancer and what side effects occur. About…

This study tests whether giving a combination of two medicines (esketamine and dexmedetomidine) during hip fracture surgery can improve sleep quality afterward in patients aged 65 and older. Half of the 96 participants will receive the drug combo, and the other half will receive …

This study tests whether a special brain-wave monitor (MGRNOX) can help doctors give less opioid pain medicine during gallbladder surgery. About 112 adults having laparoscopic cholecystectomy will be randomly assigned to standard care or MGRNOX-guided anesthesia. The goal is to s…

This study aims to find the best dose of remifentanil, a short-acting opioid, to prevent sudden changes in heart rate and blood pressure when a breathing tube is placed during anesthesia. About 99 adults having planned surgery will receive either lidocaine or sufentanil along wit…

This study aims to find the exact amount of ciprofol needed to put people under anesthesia for thyroid surgery. About 101 adults will take part, and their level of consciousness will be carefully measured using standard sedation scores and brain wave monitoring. The goal is to im…