New study seeks perfect anesthesia dose for thyroid surgery patients
NCT ID NCT07294989
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the best dose of a sedative called ciprofol for people having thyroid surgery. About 101 adults will receive this medicine to put them to sleep, and researchers will track how their brain activity changes. The goal is to find the exact amount needed for safe and effective anesthesia, and to see if a brain monitor can reliably measure sedation levels.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 101 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients undergoing elective thyroidectomy at Peking University Shenzhen Hospital
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-65 years * Scheduled for elective thyroidectomy * ASA physical status classification I-II * Willing to participate and providing written informed consent Exclusion Criteria: * Recent use of sedatives or opioid analgesics * Severe hepatic or renal dysfunction defined as:Child-Pugh class C (score ≥10), Creatinine clearance \<35 mL/min ,Requiring preoperative dialysis * Significant cardiovascular comorbidities * Body mass index ≥35 kg/m² or \<18.5 kg/m² * Known hypersensitivity or adverse reactions to propofol/ciprofol * Neuropsychiatric disorders including:Alzheimer's disease,History of cerebrovascular events,Traumatic brain injury,Space-occupying brain lesions,Other significant neurological deficits
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Peking University Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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