Paul Szabolcs

This study tests whether high-dose chemotherapy followed by a stem cell transplant can help people with severe Crohn's disease that hasn't responded to other treatments. It includes up to 20 children and adults aged 10 to 60. The goal is to see if the approach is safe and can red…

This study tests a stem cell transplant using the patient's own blood cells to treat severe scleroderma (systemic sclerosis) that hasn't improved with standard drugs. The goal is to see if this high-dose therapy is safe and can stop the disease from getting worse. The trial enrol…

This study tests if a lung transplant followed by a bone marrow transplant can help people with severe lung disease (like pulmonary fibrosis or COPD) who also have bone marrow failure. The goal is to restore both lung function and blood cell production. Participants will receive …

This study is testing a less intense chemotherapy and radiation regimen before a stem cell transplant for children and young adults up to age 55 with non-cancerous blood disorders like immune deficiencies, anemias, and metabolic diseases. The goal is to see if this gentler prepar…

This study tests a stem cell transplant for people with common variable immunodeficiency (CVID) and other immune disorders. The goal is to replace the faulty immune system with a healthy donor's stem cells. Participants are aged 5 to 40 and will receive a reduced-intensity transp…

This study tracks children and adults with non-cancerous blood or immune disorders who receive a stem cell transplant using a milder chemotherapy regimen. The goal is to see how well the transplant works and to monitor side effects like graft-versus-host disease. Up to 50 partici…