National Institute Of Mental Health (nimh)
Clinical trials sponsored by National Institute Of Mental Health (nimh), explained in plain language.
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Chilling the brain: scientists probe Temperature's role in brain plasticity
Knowledge-focused CompletedThis study looked at how cooling the brain changes its response to magnetic stimulation. Healthy adults wore a cooling cap while researchers measured brain activity with TMS and EEG. The goal was to better understand brain plasticity, not to treat any disease.
Phase: NA • Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated May 01, 2026 17:42 UTC
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Brain scans reveal dopamine secrets in schizophrenia
Knowledge-focused CompletedThis study looked at how certain brain receptors (dopamine D1 and D2/3) work in people with schizophrenia compared to healthy volunteers. Researchers used special PET and MRI scans to measure these receptors. The goal was to learn more about what causes schizophrenia, which could…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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Scientists scan brains of thousands to uncover secrets of schizophrenia
Knowledge-focused CompletedThis study used advanced brain scans (MRI and MEG) to compare the brains of over 3,000 people with schizophrenia and healthy volunteers. The goal was to find differences in brain structure, chemistry, and activity that could help explain schizophrenia. No treatments or medication…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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Brain scans reveal Schizophrenia's secrets when meds are paused
Knowledge-focused CompletedThis study looked at how the brain works in people with schizophrenia when they are not taking medication. Researchers used brain scans and tests to separate the effects of the illness from the effects of the drugs. Participants stayed in the hospital for safety while their medic…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:04 UTC
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Scientists investigate the roots of PMS mood swings
Knowledge-focused CompletedThis study looked at women with PMS to better understand their symptoms. Researchers used interviews, daily mood ratings, and hormone tests to describe the condition. A smaller group with severe PMS (PMDD) was offered extra studies on hormone changes, treatments, and genetics. Th…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Scientists probe brain zaps to unlock mental health mysteries
Knowledge-focused CompletedThis study tested different ways to apply non-invasive brain stimulation (like magnetic pulses) in 83 healthy adults aged 18-65. The goal was to learn how to make these techniques more effective for diagnosing and treating brain disorders. Participants completed tasks, had brain …
Phase: NA • Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC
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Brain scans reveal dopamine secrets in Parkinson's and schizophrenia
Knowledge-focused CompletedThis study used PET scans to look at dopamine and blood flow in the brains of healthy people, people with Parkinson's disease, and those with schizophrenia. The goal was to understand how dopamine problems differ between these conditions. Over 500 participants took part, but no t…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:01 UTC