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Brain zaps and therapy: new combo tackles depression

NCT ID NCT03289923

First seen Oct 31, 2025 · Last updated Jun 13, 2026 · Updated 36 times

Summary

This study tested whether combining a non-invasive brain stimulation technique called rTMS with cognitive therapy can help treat major depression. Researchers used MRI scans to personalize the brain target for each participant. 32 adults with depression took part in daily sessions over 6 weeks, followed by check-ups for 3 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.