National Institute Of Diabetes And Digestive And Kidney Diseases (niddk)
Clinical trials sponsored by National Institute Of Diabetes And Digestive And Kidney Diseases (niddk), explained in plain language.
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Scientists test drug duo to halt type 1 diabetes in its tracks
Disease control OngoingThis study is testing whether giving two immune-suppressing drugs (rituximab-pvvr followed by abatacept) is better than one drug alone for people recently diagnosed with type 1 diabetes. The main goal is to see if the combination helps the body preserve its own ability to make in…
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Apr 03, 2026 21:40 UTC
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New drugs aim to slow type 1 diabetes in its tracks
Disease control OngoingThis study is testing two experimental drugs, abrocitinib and ritlecitinib, to see if they can help preserve the body's remaining insulin-producing cells in people recently diagnosed with type 1 diabetes. The trial involves 78 participants aged 12-35 who were diagnosed within the…
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Lifeline drug access for rare fat disorder patients
Disease control OngoingThis study provides continued access to the drug metreleptin for people with partial lipodystrophy, a rare condition that causes severe diabetes and high blood fats. It is for patients who have already benefited from the drug in past NIH studies but cannot get it through regular …
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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Lifeline for rare disease patients denied access to vital drug
Disease control OngoingThis study provides continued access to the drug metreleptin for people with a rare condition called generalized lipodystrophy who have previously received it through NIH research and cannot get it through normal channels in their home country. It aims to monitor the long-term sa…
Phase: PHASE3 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Decade-Long study tracks patients after hepatitis c cure
Knowledge-focused OngoingThis study follows people who have been cured of chronic hepatitis C for up to 10 years to understand their long-term health. Researchers want to see if cured patients still develop liver complications, cancer, or other health problems over time. The study involves regular check-…
Phase: PHASE4 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Researchers track Decades-Long impact of diabetes on native american kidneys
Knowledge-focused TerminatedThis study follows American Indians with type 2 diabetes to understand the long-term effects of a previous kidney treatment trial. Researchers are observing how kidney disease progresses over many years through regular tests, scans, and optional biopsies. No new treatment is prov…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC
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Scientists hunt for diabetes genes in major study
Knowledge-focused TerminatedThis study aims to discover the specific genes and biological pathways that influence a person's risk of developing type 2 diabetes and related health problems like kidney and eye disease. Researchers will collect health information, blood samples, and genetic data from over 2,00…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC