National Eye Institute (nei)

This study reviews medical records from the past 20 years to see how well a freezing treatment called trans-scleral cryotherapy works for retinal hemangioblastoma, a rare eye tumor often linked to von Hippel-Lindau disease. Researchers will look at outcomes like tumor control and…

This study follows 68 people aged 12 and older who have changes in the ABCA4 gene, which can cause vision loss. Over 10 years, researchers will monitor how the disease progresses through eye exams, blood tests, and skin samples. No treatment is given; the goal is to gather inform…

This study follows about 110 people who were in the original AREDS or AREDS2 studies for an additional 5 years. The goal is to observe how age-related macular degeneration and cataracts naturally progress over time. Participants get a yearly eye exam and a check-in phone call. No…

This study follows 57 people with age-related macular degeneration (AMD) for up to 5 years to see how their eyes adjust to darkness. Participants, who completed an earlier study, will have regular eye exams and dark adaptation tests. The goal is to better understand how AMD progr…

This study follows 217 adults aged 50 and older with or without early to middle dry age-related macular degeneration (AMD) for up to 5 years. Researchers measure how quickly the eyes recover in dim light using a dark adaptation test. The goal is to see if this simple test can hel…

This study looks at X-linked juvenile retinoschisis, an inherited eye disease that causes vision loss mainly in young males. Researchers want to understand why and how the retina splits, leading to worsening sight over time. Participants include patients aged 9 months and older, …