National Eye Institute (nei)
Clinical trials sponsored by National Eye Institute (nei), explained in plain language.
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Scientists search for clues in inherited vision loss disease
Knowledge-focused OngoingThis study aims to better understand X-linked juvenile retinoschisis (XLRS), an inherited eye disease that causes progressive vision loss primarily in young males. Researchers will examine patients and their family members to learn how specific genetic changes relate to the sever…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Scientists track vision loss for a decade to find future cures
Knowledge-focused OngoingThis study aims to understand how specific gene mutations cause inherited eye diseases like Stargardt disease, which lead to vision loss. Researchers will follow about 68 people with these mutations for 10 years, collecting blood and skin samples and tracking their eye health. Th…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists track eye health for decades in landmark study extension
Knowledge-focused OngoingThis study continues tracking the eye health of people who participated in two previous major eye research projects. Researchers follow participants annually for five years to better understand how age-related macular degeneration and cataracts naturally progress over time. The s…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists track how aging eyes lose night vision
Knowledge-focused OngoingThis study follows 57 people with age-related macular degeneration (AMD) for five more years to understand how their eyes adjust to darkness over time. Participants who completed an earlier study will have regular eye exams and vision tests. The goal is to learn how changes in ni…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Doctors dig through decades of records to crack code on rare eye tumor treatment
Knowledge-focused OngoingThis study looks back at 20 years of medical records from people who received a freezing treatment for rare retinal tumors. Researchers want to understand how well the treatment worked and what side effects occurred. The goal is to learn from past experience to improve future car…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Scientists track night vision to predict eye disease progression
Knowledge-focused OngoingThis 5-year study aims to understand if measuring how quickly eyes adjust to darkness can help identify and monitor early to intermediate stages of dry age-related macular degeneration (AMD). Researchers will follow about 240 participants, some with varying stages of AMD and some…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC