National Eye Institute (nei)
Clinical trials sponsored by National Eye Institute (nei), explained in plain language.
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Can an antibiotic save your sight? new study tests minocycline for blinding eye disease
Disease control CompletedThis study tested whether the antibiotic minocycline, taken as a pill twice daily for 3 years, could safely slow the growth of geographic atrophy—an advanced form of age-related macular degeneration that causes blind spots. Thirty-seven adults aged 55 and older with geographic at…
Phase: PHASE2 • Sponsor: National Eye Institute (NEI) • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Eye tests under the microscope: new study checks accuracy for retinitis pigmentosa
Knowledge-focused CompletedThis study looked at how well different eye tests can measure changes in retinitis pigmentosa (RP), a group of eye diseases that cause blindness. Researchers tested 49 people with RP and healthy volunteers using vision tests, eye exams, and blood samples over two visits. The goal…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 26, 2026 08:01 UTC
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Eye study tracks vision loss over years without offering treatment
Knowledge-focused CompletedThis study followed 20 adults aged 55 and older with geographic atrophy, an advanced form of age-related macular degeneration that causes central vision loss. Researchers measured how the area of damage in the eye changed over nearly 4 years using special eye images. The goal was…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 26, 2026 07:59 UTC
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Could Mom's pregnancy exposures cause this eye defect?
Knowledge-focused CompletedThis study investigates whether things a mother is exposed to during early pregnancy might cause uveal coloboma, a rare eye malformation present at birth. Researchers surveyed mothers of affected children about their health, medications, and habits during the first trimester. The…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 26, 2026 07:56 UTC
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6,618 DNA samples donated to unlock secrets of rare eye diseases
Knowledge-focused CompletedThis study created a national DNA and blood bank for inherited eye diseases like retinitis pigmentosa. Over 6,600 participants donated a blood sample and had an eye exam. The goal was to help researchers find the genetic causes of these conditions and speed up the development of …
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 26, 2026 07:27 UTC
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Eye study aims to unlock secrets of macular degeneration
Knowledge-focused CompletedThis study followed 26 adults aged 55 and older with early age-related macular degeneration (AMD) or healthy eyes for up to 5 years. Researchers used eye exams, imaging, and vision tests to track changes in the retina and understand how the disease progresses. The goal was to lea…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Scientists probe gut bugs for clues to eye disease
Knowledge-focused CompletedThis study looked at the natural bacteria in the gut of people with and without uveitis, an inflammatory eye disease. Researchers collected stool and blood samples and performed eye exams to see if gut bacteria differ between the two groups. No treatment was given; the goal was s…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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Eye inflammation biobank seeks clues in genes and tissue
Knowledge-focused CompletedThis study collected blood, tissue, and other samples from 343 people with uveitis (a serious eye disease) to learn why some people get it and how they respond to treatment. Participants were followed for up to 10 years with eye exams and tests. The goal was to gather information…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC