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Could a common diabetes drug protect eyesight in genetic eye disease?

NCT ID NCT04545736

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 25 times

Summary

This study tests whether metformin, a pill used for diabetes, can safely slow vision loss in people with ABCA4 retinopathy (including Stargardt disease). About 56 participants aged 12 and older will take metformin daily for 24 months. Researchers will measure changes in the retina and track side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109-0624, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.