Mount Sinai Hospital, Canada

This study tests whether giving two medicines (acetaminophen and ibuprofen) together works better than ibuprofen alone to close a common heart blood vessel that fails to close after extremely premature birth. About 310 babies born before 27 weeks will be enrolled. The goal is to …

This study is testing whether a carefully designed diet can change the gut bacteria of people with active ulcerative colitis and reduce disease activity. Researchers will enroll 20 adults with mild to moderate disease. Participants will follow the study diet and be monitored for …

This study tests whether time-restricted eating (eating only during a set window each day) can help preserve insulin-making cells and improve blood sugar control in people with type 2 diabetes who are overweight. About 112 adults will be assigned to either a time-restricted eatin…

This study tests whether a presacral nerve block can reduce pain after total laparoscopic hysterectomy. About 60 women will receive either the nerve block or a placebo (sham) injection. The main goal is to measure pain levels 3 hours after surgery using a simple 0-10 pain scale.

This study looks at what happens when people stop taking the weight-loss drug semaglutide. It compares two strategies: stopping all at once versus slowly reducing the dose. The goal is to see which approach helps maintain weight loss and heart health. About 98 adults who have alr…

This study tests a 'Digital Bridge' that connects communication tools already used by hospitals and family doctors to improve care for older adults with multiple chronic conditions. The goal is to make hospital-to-home transitions smoother and reduce the risk of readmission. Rese…

This study looks at whether watching short educational videos about sarcoma before a first doctor's appointment helps patients and their caregivers feel more informed and satisfied. About 100 adults with advanced sarcoma (or their caregivers) who have not yet had treatment will w…