Mesoblast, Inc.

This study tested whether injecting donor stem cells into the heart could help people with chronic heart failure. 565 adults with heart failure received either the stem cells or a sham procedure. The goal was to see if the cells could reduce heart-related emergencies like hospita…

This study looked at the safety of giving extra doses of a stem cell drug called Remestemcel-L to 73 people with moderate-to-severe Crohn's disease that didn't respond to standard treatments. All participants had already received this treatment in an earlier study. The goal was t…

This study tested whether infusions of adult stem cells (PROCHYMAL) could help people with moderate-to-severe Crohn's disease who had not responded to standard treatments. Participants received four intravenous doses over two weeks. The goal was to see if the stem cells could saf…

This study tested a stem cell treatment called PROCHYMAL in 63 people recently diagnosed with type 1 diabetes. The goal was to see if the treatment could safely help the body keep making some of its own insulin, reducing the need for injected insulin. Participants received multip…

This study tested a stem cell product called Prochymal in 11 patients with severe graft-versus-host disease (GVHD) that did not respond to standard treatments. The goal was to see if the stem cells could safely improve or resolve GVHD symptoms. The approach involved infusing adul…

This study tested a single intravenous infusion of stem cells (PROCHYMAL) in 220 adults who had their first heart attack within the prior week. The goal was to see if the stem cells could safely improve heart function and reduce damage. Participants were randomly assigned to rece…

This study tested whether infusions of special stem cells (PROCHYMAL) could help people with moderate-to-severe Crohn's disease who had already improved with an earlier stem cell treatment. The goal was to see how long the benefit lasts and if a repeat infusion can bring back imp…

This study tested whether a single intravenous infusion of PROCHYMAL stem cells is safe and can help people with moderate to severe COPD. 62 participants received either stem cells or a placebo and were followed for two years. The main goals were to check for side effects and mea…