Mesoblast, Inc.

This study tested a stem cell treatment (rexlemestrocel-L) in 565 adults with chronic heart failure. The goal was to see if injecting these cells into the heart could reduce serious heart events like hospitalizations or death. Participants were randomly assigned to receive either…

This study tested whether multiple infusions of a stem cell product called PROCHYMAL could safely help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. The trial enrolled 63 participants aged 12 to 35 who had been diagnosed within the…

This study tested whether infusions of adult stem cells (PROCHYMAL) could help people with moderate-to-severe Crohn's disease who did not get better with standard treatments. About 330 adults received four intravenous doses over two weeks. The main goal was to achieve disease rem…

This study tested a single intravenous infusion of stem cells (PROCHYMAL) in 220 adults who had their first heart attack within the past week. The goal was to see if the stem cells could safely improve heart function and reduce damage. Participants were randomly assigned to recei…

This study tested a stem cell treatment called Prochymal in 11 people with severe graft-versus-host disease (GVHD), a life-threatening complication after a bone marrow transplant. The treatment was given to patients whose GVHD did not improve with standard therapies. The goal was…

This study tested whether infusions of special stem cells (PROCHYMAL) could help people with moderate-to-severe Crohn's disease who had already improved with an earlier stem cell treatment. The goal was to see how long the benefit lasts and if a repeat infusion can bring back imp…

This study looked at the safety of giving PROCHYMAL (a stem cell therapy) again to 73 adults with moderate-to-severe Crohn's disease that did not get better with standard treatments. Participants had already received PROCHYMAL in a previous study. The goal was to see if retreatme…

This study tested whether a single intravenous infusion of PROCHYMAL stem cells is safe and can help people with moderate to severe COPD. 62 participants received either stem cells or a placebo and were followed for two years. The main goals were to check for side effects and mea…