Stem cell therapy aims to save Insulin-Making cells in new diabetes patients

NCT ID NCT00690066

First seen Mar 23, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This study tested whether multiple infusions of a stem cell product called PROCHYMAL could safely help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. The trial enrolled 63 participants aged 12 to 35 who had been diagnosed within the past 20 weeks. The main goal was to see if the treatment could maintain or improve C-peptide levels, a marker of insulin production, compared to a placebo.

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Contacts and locations

Locations

  • AM Diabetes & Endocrinology Center

    Bartlett, Tennessee, 38133, United States

  • American Health Research, Inc.

    Charlotte, North Carolina, 28207, United States

  • Clinical and Transitional Science Institute

    Milwaukee, Wisconsin, 53226, United States

  • Cumberland Valley Endocrinology

    Carlisle, Pennsylvania, 17015, United States

  • Desert Endocrinology CRC

    Henderson, Nevada, 89052, United States

  • Diabetes Research Institute

    Miami, Florida, 33136, United States

  • Nevada Alliance Against Diabetes

    Las Vegas, Nevada, 89101, United States

  • Optimum Clinical Research, Inc.

    Salt Lake City, Utah, 84102, United States

  • Providence Health Partners - Center for Clinical Research

    Dayton, Ohio, 45439, United States

  • Scripps Whittier Diabetes Institute

    La Jolla, California, 92037, United States

  • Stanford University

    Stanford, California, 94305, United States

  • The Lindner Clinical Trial Center

    Cincinnati, Ohio, 45219, United States

  • The Strelitz Diabetes Center, Eastern VA Medical School

    Norfolk, Virginia, 23510, United States

  • The University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Alabama, Division of Endocrinology & Metabolism

    Birmingham, Alabama, 35294, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Kentucky

    Lexington, Kentucky, 40502, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of North Carolina Diabetes Care Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Wisconsin Health- West Clinic

    Madison, Wisconsin, 53717, United States

Conditions

Explore the condition pages connected to this study.