Medical University Of Vienna

This phase IIa trial tests whether OM336, a T-cell engager, can safely reduce the immune antibodies that make it hard for highly sensitized kidney patients to find a compatible donor. Twelve adults awaiting a kidney transplant will receive weekly injections for four weeks, with a…

People on maintenance hemodialysis face a high risk of heart disease, and standard cholesterol drugs often fail to help. This trial tests whether high-dose fish oil (4 grams daily for 8 weeks) can improve the function of HDL, the 'good' cholesterol, which may become faulty in kid…

This pilot study tests a new dialysis catheter coated with Endexo technology, designed to resist blood clots and reduce infections. Researchers will compare its performance to older catheters in 50 adults with end-stage kidney disease. If successful, it could improve quality of l…

This study compares two common ways to access the blood for dialysis: a tunneled catheter (a tube placed in a large vein) versus a surgically created fistula (connecting an artery to a vein). The trial will enroll 220 patients aged 60 or older (or younger but with multiple health…

This study compares a gel made from cross-linked hyaluronic acid (a natural substance) to standard bone grafting for preserving the jawbone after a tooth is pulled. Forty-eight adults needing a tooth extraction and later a dental implant will be randomly assigned to receive eithe…

This study tests if a store-bought mouthwash can reduce a parasite called Entamoeba gingivalis in the mouth. This parasite can damage gums and cause inflammation. Forty healthy adults with the parasite will use the mouthwash twice daily for a week, and researchers will measure ch…

This pilot study tests whether a personalized lifestyle program combining workshops, remote coaching, and a smartphone app can help adults aged 55-75 at risk for dementia adopt healthier habits. 300 participants will either receive tailored guidance or standard advice. The main g…

Endometriosis causes chronic pelvic pain and painful periods, and current treatments do not work for everyone. Researchers are testing whether desloratadine, an antihistamine usually taken for allergies, can reduce pain and improve quality of life. The trial enrolls 60 women aged…

Dry eye can appear or worsen after cataract surgery, causing discomfort and blurry vision. Researchers at the Medical University of Vienna are testing whether a hyaluronic acid gel placed into the tear drainage duct of one eye can help retain tears and reduce dry eye. Each partic…

This trial tests whether real-time video guidance from a remote obstetric expert helps healthcare teams manage shoulder dystocia, a rare and time-critical birth complication, better than a standard visual checklist. Teams of at least two providers will handle a simulated emergenc…

This study looks at whether new, non-invasive tests can predict bronchopulmonary dysplasia (BPD), a common lung complication in extremely preterm infants. Researchers will monitor 140 babies born before 26 weeks of gestation using lung and diaphragm ultrasounds, respiratory funct…

This study looks at whether ventilating only one lung during heart-lung bypass surgery can reduce fluid buildup and lung damage in high-risk patients. Forty-five older adults having major elective heart surgery will take part. The goal is to see if this approach leads to better l…

This early-phase trial investigates whether m-Cresol, a preservative used in many injectable medications like insulin, causes pain at the injection site. Eighteen healthy volunteers will receive three injections in their belly: one with a low concentration of m-Cresol, one with a…

This study will compare 40 nearsighted children to 40 children with normal vision, all aged 8 to 13. Researchers will measure how much oxygen the retina uses and look at blood flow and eye structure. The goal is to learn whether low oxygen plays a role in causing myopia. No treat…

This study investigates how insulin delivered through the nose changes dopamine signaling and energy use in the brains of people with first-episode psychosis. Researchers will compare brain scans and chemical levels in 46 participants (patients and healthy volunteers) after recei…

This study will observe 250 heart surgery patients in the ICU to see how giving fluids affects vein congestion and kidney function. Doctors will use ultrasound to measure vein congestion and track kidney injury over the first week. The goal is to find better ways to manage fluids…