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One-Lung breathing during heart bypass may cut fluid buildup

NCT ID NCT07612709

Knowledge-focused Sponsor: Medical University of Vienna Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether ventilating only one lung during heart-lung bypass surgery can reduce fluid buildup and lung damage in high-risk patients. Forty-five older adults having major elective heart surgery will take part. The goal is to see if this approach leads to better lung function after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward a safer way to protect lungs during heart surgery, potentially reducing complications.
What could go wrong
This is a very small, early-stage study (45 people) that only measures short-term effects. It may not lead to a proven treatment or apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Jul 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients at increased risk for postoperative pulmonary complications * Major elective cardiac surgery * Prolonged duration of cardiopulmonary bypass * Patients older than 65 years of age * Informed consent Exclusion Criteria: * Emergency * Urgent procedures * Patients with implanted pacemakers * Patients with internal cardioverter/defibrillators * Decompensated cardiac disease * Pulmonary disease * Recent pneumonia * Need for temporary perioperative mechanical support * Patients not willing to participate * Treatment with inhaled nitric oxide

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Conditions

The condition(s) this trial relates to.

pulmonary edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Biomarkers of vascular endothelial injury Cardiopulmonary bypass Chest X-ray for clinical evaluation Electrical impedance tomography (EIT) High-risk cardiac patients Lung compliance Lung ultrasound Lung water assessment Lung-protective ventilation Oxygenation indices Pulmonary complications in surgical patients Single-lung ventilation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • General Hospital Vienna

    Vienna, State of Vienna, 1090, Austria

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