Lung rehab program aims to get blood clot survivors back on their feet
NCT ID NCT04615130
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 6-week outpatient pulmonary rehabilitation program helps people with post-PE syndrome (lingering symptoms after a pulmonary embolism) walk farther and breathe better. About 48 adults who had a pulmonary embolism 12 to 36 weeks earlier will be randomly assigned to start rehab right away or wait. The main goal is to see if the program improves walking distance in 6 minutes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2021
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Post-PE syndrome (except patients previously diagnosed with CTEPH) diagnosed by any of the following: * Post-PE functional impairment criteria * Post-PE Cardiac Impairment criteria * Chronic Thromboembolic Disease criteria * Possibility of starting rehabilitation between 12 and 36 weeks after the initial event of PE Exclusion Criteria: * CTEPH diagnosis * Chronic pulmonary diseases: COPD, interstitial lung diseases, asthma (only patients with severe asthma defined as a FEV1 ≤ 80% will be excluded), a statement on COVID-19 was amended due to the pandemic # * Active cancer * Pregnancy * Myocardial infarction or cardiac surgery one year prior to inclusion * Congenital heart disease, congestive heart failure * History of stroke * Any previous inpatient or outpatient PR Additional criteria that are absolute contraindications for pulmonary rehabilitation * Acute and decompensated disease states with severe functional restrictions of various organ systems (e.g. heart, kidney and liver insufficiency, unstable angina pectoris, hemodynamically unstable arrhythmias, acute spinal cord injury, untreated hormonal disorders, acute psychological disorders) * open tuberculosis * active infectious diseases and acute inflammatory processes * Stressful and time-consuming therapy that significantly impair the ability to rehabilitate (e.g. chemotherapy or radiation therapy after malignancy) * Participants who are not sufficiently resilient due to physical or mental impairment and / or cannot be mobilized and therefore cannot actively use the rehabilitation facility * lack of motivation for therapy * massive incontinence * drugs and alcohol addiction
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Therme Wien Med
RECRUITINGVienna, Austria
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Other studies related to the condition(s) this trial covers.
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