Medical University Of South Carolina

This early-stage trial tested the safety and effectiveness of combining two drugs, tarloxotinib and sotorasib, for patients with advanced non-small cell lung cancer driven by a specific genetic change called KRAS G12C. The study was for patients whose cancer had continued to grow…

This study aimed to see if a 24-hour drug infusion works as well as the standard 72-hour infusion to prevent re-bleeding in patients with liver cirrhosis. It involved adults who had a procedure to stop bleeding from swollen veins in their esophagus. The goal was to determine if t…

This study tested an experimental vaccine called PROSTVAC-V/F to see if it could stop prostate cancer from coming back after surgery in men at high risk of relapse. The trial was terminated early and enrolled only 33 participants before ending. Researchers aimed to measure how lo…

This study tested whether a grape seed extract called OPC could reduce certain food-related substances (AGEs) in the blood of prostate cancer patients receiving hormone therapy. Researchers wanted to see if lowering AGE levels might help control cancer. The trial was terminated e…

This study tested whether an existing FDA-approved Parkinson's drug called istradefylline could help improve motivation and reduce apathy in people with Parkinson's disease. Over 12 weeks, researchers measured if patients became more engaged in physical activities and hobbies. Th…

This study tested whether the prescription sleep medication suvorexant could help breast cancer survivors who have trouble sleeping. A small group of survivors with significant insomnia were randomly assigned to receive either the drug or a placebo pill, along with basic sleep ad…