Medical University Of South Carolina

This study tested a combination of two drugs, tarloxotinib and sotorasib, in adults with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. Participants had already tried other treatments, including a KRAS-targeting drug, and their cancer had…

This study looked at whether a 24-hour infusion of the drug octreotide works as well as a 72-hour infusion to prevent early rebleeding in people with liver cirrhosis who had bleeding esophageal varices treated with endoscopic banding. The trial enrolled 34 adults with cirrhosis a…

This study tested a treatment called PROSTVAC-V/F in 33 men who had their prostate removed but were at high risk of the cancer returning. The goal was to see if the treatment could keep cancer from coming back. The study was stopped early, so results are limited, but the informat…

This study looked at whether a drug called OPC could lower AGE levels in men with prostate cancer who are receiving hormone therapy (androgen deprivation therapy). AGEs are substances that can build up in the body and may cause health problems. The study planned to enroll 41 part…

This study tested whether the sleep medication suvorexant (20 mg) could help breast cancer survivors who have trouble sleeping. Participants were postmenopausal women currently taking hormone therapy. The trial compared suvorexant to a placebo, with both groups also learning abou…

This study tested a device that uses cold (non-thermal) plasma to treat common skin bumps like warts and molluscum in children and teens aged 4 to 21. Over up to one year of monthly treatments, doctors checked how many bumps cleared up, changed in size, or had no response. The go…

This study looked at whether having a certified therapy dog in the room helps children aged 3-7 feel less anxious and behave better when getting a numbing shot at the dentist. About 41 kids took part, and researchers compared those with a dog present to those without. The study w…

This study looked at whether istradefylline, a drug already approved for motor symptoms in Parkinson's disease, could also improve apathy and motivation. Apathy is a common issue where people lose interest and drive. The study planned to follow 8 participants for 12 weeks, but it…