Leiden University Medical Center
Clinical trials sponsored by Leiden University Medical Center, explained in plain language.
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Virtual coach aims to kick smoking and boost activity
Disease control CompletedThis study tested a virtual coach designed to help adults quit smoking and become more physically active. About 100 participants used the coach for around 16 weeks. Researchers measured how well people liked and used the program, and checked if it helped them change their habits.
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Disease control
Last updated Jun 22, 2026 12:08 UTC
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New clamping method could save preterm brains
Disease control CompletedThis study tested a new way of clamping the umbilical cord in very preterm babies (born before 30 weeks). Instead of clamping after a fixed time, doctors waited until the baby was stable—heart rate above 100 and oxygen levels normal. The goal was to see if this approach helps mor…
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Disease control
Last updated Jun 22, 2026 11:59 UTC
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New algorithm could spare cancer patients unnecessary CT scans for blood clots
Diagnosis CompletedThis study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Diagnosis
Last updated Jun 23, 2026 11:56 UTC
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New chest pain rule could cut unnecessary hospital trips
Diagnosis CompletedThis study tested a decision rule that combines a checklist (Marburg Heart Score) with a rapid blood test (high-sensitive troponin I) to help general practitioners decide if patients with new chest pain need hospital referral. About 946 adults with acute chest pain took part. The…
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Diagnosis
Last updated Jun 16, 2026 12:53 UTC
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Simple chat with nurse could soothe dry mouth for the frail
Symptom relief CompletedThis study tested a nurse-led education program for dry mouth in 70 patients with life-limiting conditions or frailty. Nurses used guidelines to discuss causes and treatments with patients, creating a personalized plan. The goal was to see if this approach reduces dry mouth sever…
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Symptom relief
Last updated Jun 23, 2026 11:59 UTC
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Could less steroid before chemo be safer and just as effective?
Symptom relief CompletedThis study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel can prevent allergic reactions with fewer side effects. The standard high dose can cause problems like high blood sugar, mood changes, and weakened immunity. Resea…
Phase: PHASE1 • Sponsor: Leiden University Medical Center • Aim: Symptom relief
Last updated Jun 22, 2026 12:04 UTC
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Doctor training may ease insomnia, study finds
Symptom relief CompletedThis study looked at whether teaching primary care doctors better ways to treat insomnia can help their patients sleep better. About 485 patients with insomnia symptoms completed surveys. Researchers compared patients whose doctors received special training with those getting usu…
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Symptom relief
Last updated Jun 12, 2026 12:04 UTC
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New model helps doctors decide when to transfuse preterm babies
Knowledge-focused CompletedThis study looked at over 1,000 preterm infants born before 34 weeks who had very low platelet counts. Researchers created a model to predict each baby's risk of major bleeding or death, with or without a platelet transfusion. The goal is to help doctors make personalized decisio…
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:46 UTC