Latin American Cooperative Oncology Group

This study looks at whether some women with HER2-positive early breast cancer can be treated with a combination of two targeted drugs (pertuzumab and trastuzumab) without needing chemotherapy. The researchers are selecting patients whose tumors are strongly driven by the HER2 pat…

This study aimed to see if a person's race or ethnicity changed how well a drug combination (niraparib, abiraterone acetate, and prednisone) worked for a certain type of advanced prostate cancer. It planned to enroll Black, Hispanic, White, and Native American men whose cancer ha…

This study tests a combination of three drugs (amivantamab, lazertinib, and pemetrexed) as a first treatment for people with advanced lung cancer that has a specific genetic change (EGFR mutation). The goal is to see if this combination can keep the cancer from growing for at lea…

This study tests a new approach called extreme bipolar androgen therapy for men with advanced prostate cancer that no longer responds to standard hormone therapy. The treatment combines a drug that blocks testosterone (darolutamide) with high doses of testosterone itself, aiming …