Institute Of Oncology Ljubljana

This study tests a two-step treatment for adults with locally advanced pancreatic cancer that cannot be removed by surgery. First, patients receive standard chemotherapy. If the cancer does not spread, they then get high-precision radiation (SBRT) to the tumor, followed by more c…

This study tests a treatment called electrochemotherapy for women whose vulvar cancer has come back. It combines a chemotherapy drug (bleomycin) with short electric pulses to help the drug enter cancer cells more effectively. The goal is to shrink tumors and reduce the need for e…

This study is testing a highly precise radiation technique called SBRT for people with cancer that has spread to the spine. The goal is to see how safe and effective this treatment is when used in regular hospital practice. About 100 adults will take part, and researchers will tr…

This study tests whether giving the numbing drug lidocaine through a vein during colon cancer surgery can reduce pain, lower the need for strong painkillers, and help the bowels start working again sooner. About 100 adults having laparoscopic colon cancer surgery will be randomly…

This study is testing a web-based application that lets cancer patients report side effects from radiation therapy in real time. About 30 people with gynecologic, urologic, or breast cancer will use the app to answer simple questionnaires. Their responses are sent securely to the…

This study looks at whether giving lidocaine (a numbing medicine) or high-dose dexamethasone (a strong anti-inflammatory) during colon cancer surgery can help the immune system recover better afterward. About 100 adults having colon cancer surgery will be randomly assigned to rec…

This study looks at how well a simple questionnaire (SARC-F) can identify gastrointestinal cancer patients who are at risk for sarcopenia—a condition where they lose muscle mass and strength. Sarcopenia can lead to more complications and worse outcomes, even in patients who seem …

This study follows 368 colorectal cancer survivors aged 25 to 65 to see how their quality of life changes 6, 12, and 24 months after finishing treatment. Researchers will use questionnaires to measure physical, mental, and social well-being, as well as any long-term side effects.…

This study is looking at whether clusters of tumor cells found in the blood can help predict how well treatment works in people with high-risk early breast cancer. Researchers will follow 130 participants to see if those with these cell clusters have different outcomes. The goal …

This study looks at how effective first-line immunotherapy is for people with metastatic melanoma treated at the Institute of Oncology Ljubljana in Slovenia. Researchers will track tumor shrinkage, time to progression, and side effects, and analyze blood, stool, and body fluids t…

This study looks at how much protein people with chronic intestinal failure need when they get nutrition through a vein at home. Researchers will measure how the body uses protein and check gut bacteria function. The goal is to make personalized nutrition mixtures for better heal…

This study checks how many people with gastrointestinal cancer are at risk for sarcopenia—a condition where muscles weaken and shrink. Researchers will use a simple questionnaire (SARC-F) before and during cancer treatment. The goal is to find those at risk early so they can get …

This study looks at how chemotherapy affects memory and thinking in people with a type of blood cancer called diffuse large B-cell lymphoma. Researchers will test cognitive function at the start, after the first chemo cycle, and one year later. They also analyze spinal fluid in s…

This study looks at how well women with early-stage, hormone-positive breast cancer take their prescribed medications (aromatase inhibitors with or without abemaciclib). About 319 participants will be followed for 6 months to see if those on the combination therapy have lower adh…

This study looks at how electrochemotherapy—a treatment that uses electric pulses to help chemotherapy drugs enter tumor cells—changes the environment around melanoma skin tumors. Researchers will collect tissue samples from 150 adults with melanoma before and after treatment to …

This study is looking at how effective immunotherapy is as a first treatment for metastatic melanoma that has spread. Researchers will check if a marker called PD-L1, found in tumors and blood, can help predict who will respond well. About 100 adults with advanced melanoma will t…