Institut Paoli-calmettes
Clinical trials sponsored by Institut Paoli-calmettes, explained in plain language.
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New drug combo fails to advance in resistant breast cancer trial
Disease control TerminatedThis study tested a combination of two oral drugs, BKM120 and lapatinib, in people with a specific type of advanced breast cancer (HER2-positive) that had stopped responding to the standard drug trastuzumab. The goal was to see if the combination was safe and could shrink tumors.…
Phase: PHASE1, PHASE2 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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Scientists hunt for clues in breast cancer genes
Knowledge-focused TerminatedThis study aimed to find genetic and protein changes in breast cancer that might predict how the disease behaves. Researchers planned to study 749 adults with breast cancer, looking at gene activity and mutations. The study was terminated early, so results are limited.
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC