Institut Paoli-calmettes
Clinical trials sponsored by Institut Paoli-calmettes, explained in plain language.
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Kidney removal after immunotherapy may offer cure for select patients
⭐️ CURE ⭐️ Recruiting nowThis study tests whether removing the kidney after successful immunotherapy can help patients with metastatic kidney cancer stop all treatment and stay cancer-free. About 60 adults whose tumors have shrunk significantly with immunotherapy will either have surgery and stop therapy…
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: ⭐️ CURE ⭐️
Last updated Jun 15, 2026 19:05 UTC
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New hope for tough leukemia: DASATINIB trial targets Non-Responders
Disease control Recruiting nowThis study tests a drug called DASATINIB in people with acute myeloid leukemia (AML) whose cancer did not improve after standard treatment with VENETOCLAX and AZACITIDINE. About 35 adults who cannot have strong chemotherapy will take DASATINIB for up to 3 months. Doctors will che…
Phase: PHASE2 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated Jun 16, 2026 12:52 UTC
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New hope for advanced cancers? first human trial of IPH5301 begins
Disease control Recruiting nowThis early-phase study tests a new drug called IPH5301 in people with advanced solid tumors that have spread. The goal is to find a safe dose and see if it works alone or with chemotherapy and another drug. About 27 adults with certain cancers like breast, lung, or stomach cancer…
Phase: PHASE1 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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Leukemia treatment breakthrough: could less be more?
Disease control Recruiting nowThis study tests whether adults with acute myeloid leukemia (AML) who are doing well on a two-drug chemotherapy combination (venetoclax and azacitidine) can safely stop or reduce their treatment. About 50 participants will stop the drugs and be closely monitored for relapse. Thei…
Phase: PHASE2 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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Lung cancer clue hunt: why do only 40% respond to immunotherapy?
Knowledge-focused Recruiting nowThis study aims to find biological markers (biomarkers) in the blood and tumors of people with non-small cell lung cancer that can predict whether immunotherapy will work. Researchers will compare these markers between people whose cancer responds and those whose does not. The go…
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC