Institut Paoli-calmettes

This study tested a new type of stem cell transplant called microtransplantation in 25 adults with myeloid blood cancers (acute myeloid leukemia or myelodysplastic syndromes) who could not have a standard transplant. Unlike regular transplants, this approach uses partially matche…

This study compared two surgical approaches for low rectal cancer: a newer method using a scope through the anus (transanal) versus the standard laparoscopic approach through the abdomen. 226 adults with non-spread rectal cancer were randomly assigned to one of the two surgeries.…

This study looked at whether taking an oral hormone therapy called apalutamide for 6 months could slow down low-risk prostate cancer and delay the need for more aggressive treatments like surgery or radiation. 93 men on active surveillance (watching the cancer without immediate t…

This study looked at whether reducing the use of strong antibiotics in cancer patients with sepsis or septic shock is safe and effective. Researchers compared stopping or narrowing antibiotics early versus continuing them as usual. The goal was to see if this approach could lower…

This early-phase study tested whether giving specially selected donor immune cells (NK cells) soon after a stem cell transplant is safe for people with blood cancers. Seventeen patients received the cells, and researchers monitored for serious side effects within 30 days. The goa…

This study tested a new urine test called VISIOCYT to see how well it finds bladder tumors compared to standard methods. About 700 adults with suspected or follow-up bladder cancer provided urine samples before their regular cystoscopy. The goal was to measure the test's accuracy…

This study looked at 135 people with advanced lung cancer, lymphoma, or other tumors treated with immunotherapy drugs called checkpoint inhibitors. Researchers collected blood and tumor samples over time to measure immune cells and molecules that might predict whether the treatme…

This study aimed to find biological markers (biomarkers) in pancreatic tumor cells and blood that could help doctors predict how well a patient's cancer will respond to treatment. Researchers collected small tumor samples using a special ultrasound-guided needle and also took blo…

This study looked at whether analyzing the DNA of tumors from people with advanced or metastatic solid cancers could help doctors pick a targeted treatment. Over 550 patients had their tumor samples genetically tested. The goal was to see how many patients could be matched to a t…

This study looked at 650 adults with acute leukemia, myelodysplastic syndromes, or myeloproliferative disorders. Researchers collected blood, bone marrow, skin, and cheek samples to study genetic, epigenetic, and immune features. The goal was to find factors that predict how the …