Could a short hormone course help men with low-risk prostate cancer avoid treatment?

NCT ID NCT03088124

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking an oral hormone therapy called apalutamide for 6 months could slow down low-risk prostate cancer and delay the need for more aggressive treatments like surgery or radiation. 93 men on active surveillance (watching the cancer without immediate treatment) were randomly assigned to continue surveillance alone or add the 6-month drug course. The goal was to see if the drug could safely push back the time when local treatment becomes necessary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHP Saint- Grégoire

    Saint-Grégoire, 35760, France

  • CHRU Hopital Edouard Herriot

    Lyon, 69437, France

  • Chu Hotel Dieu

    Nantes, France

  • Chu Pontchaillou

    Rennes, France

  • Chu Saint Etienne

    Saint-Etienne, 42055, France

  • Chu Tenon

    Paris, France

  • Chu de Nice

    Nice, France

  • Clinique Beau Soleil

    Montpellier, 34070, France

  • Clinique La Croix Du Sud

    Quint-Fonsegrives, France

  • Hia Sainte Anne

    Toulon, France

  • Hôpital de Cannes

    Cannes, 06400, France

  • Institut Mutualiste Montsouris

    Paris, 75014, France

  • Institut Paoli Calmettes

    Marseille, Bouches du Rhône, 13009, France

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