Promising combo for resistant breast cancer falls short – study halted
NCT ID NCT01589861
First seen Apr 25, 2026 · Last updated Jun 14, 2026 · Updated 7 times
Summary
This study tested a combination of two oral drugs, BKM120 and lapatinib, in 24 adults with HER2-positive breast cancer that had spread and no longer responded to trastuzumab. The goal was to find the safest dose and see if the combo could shrink tumors. The study was terminated early, so results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Institut Paoli-Calmettes
Marseille, 13008, France
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.